产品货号：
Z21713
中文名称：
NOTUM抗体
英文名称：
Anti-NOTUM Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NOTUM Antibody |
| 指标别名 | Protein notum homolog |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | NOTUM |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | NOTUM antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human NOTUM.The immunogen is located within amino acids 90 - 140 of NOTUM. |
| 计算分子量 | 56kDa |
| 成分 | NOTUM Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | NOTUM Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | In Drosophila,the notum gene is regulated by the Wingless pathway and encodes a secreted hydrolase that modifies heparan sulfate proteoglycans.The mammalian homolog has been shown to be able to cleave glypicans and can release GPI-anchored proteins from the mammalian cell surface.Like the Drosophilia NOTUM,the mammalian protein can act as a negative regulator of the Wnt signaling pathway.NOTUM is expressed at a low level in most mammalian tissues,although it is overexpressed in a subset of human hepatocellular carcinomas.Its transcription is regulated by beta-catenin/TCF and is a target of the Wnt signaling pathway,forming a negative feedback loop that regulates the expression and activity of the Wnt pathway. |
| Uniprot ID | Q6P988 |
| 基因名全称 | Notum pectinacetylesterase homolog (Drosophila) |
| 蛋白名全称 | Notum pectinacetylesterase homolog (Drosophila) |
| 推荐稀释比 | NOTUM antibody can be used for detection of NOTUM by Western blot at 0.5 ～ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
相关搜索：NOTUM抗体，NOTUM多抗，Anti-NOTUM Antibody